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Chamberlain AmericInn by Wyndham Conference Center

Enjoy a pleasant stay in Chamberlain at this inviting, pet-friendly hotel off I-90 near the Missouri River.

Located off I-90, this AmericInn Lodge & Suites Chamberlain - Conference Center hotel offers easy access to the Missouri River, Red Lake, and Fort Pierre National Grassland. Experience genuine hospitality with their friendly front desk staff and amenities like free WiFi, an indoor pool, and 24/7 fitness center. Whether you’re staying for business or pleasure, you’ll enjoy the proximity to South Dakota’s top attractions as well as the capital city of Pierre, which is within driving distance.


1981 East King Street, Chamberlain, South Dakota 57325

Hours of Operation

24-hour Reception Desk

Backwoods Lounge
5:00pm - 11:00pm

Go fishing, hunting, or museum hopping!

Situated along the Missouri River, this Chamberlain hotel puts you within reach of some of South Dakota’s most scenic spots. Fishing is one of the area’s main draws with opportunities on the Missouri River, Red Lake, and Fort Pierre National Grassland. Chamberlain is also home to the Lewis and Clark Interpretive Center, which features a re-creation of the expedition's 55-foot keelboat, and the Akta Lakota Museum & Cultural Center. There is also great pheasant, grouse, deer, and waterfowl hunting in the area. Plus, you can easily take a day trip to Pierre to see the capital city’s top attractions.
Aerial view of Missouri River

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